Motivation: Biocuration workflows often rely on comprehensive literature searches for specific biological entities. However, standard search
engines such as MEDLINE and PubMed Central provide an incomplete picture of the scientific literature because they do not index the increasing
amount of valuable information published in supplementary data files. Over two years, we addressed this gap by systematically extracting
text from a large proportion (85%) of these files, resulting in 35 million searchable documents. To assess the information gain provided by supplementary
data files beyond the manuscripts, we searched both for mentions of dozens of Global Core Biodata Resources (GCBRs), which are
fundamental biological databases essential for the life sciences. We searched for mentions of GCBR names and accession numbers, which
uniquely identify biological entities within these resources.
Results: The recall gain from using the supplementary data files to search for articles mentioning resource names is 6%. In addition, 97% of all
accession numbers identified were published in the supplementary data files, highlighting their increasing importance for highly specific topics
or curation pipelines. We show that the number of accession numbers published in the supplementary data files is increasing year on year, but
that 87% of these are published in Excel files. This format facilitates human readability and accessibility, but severely limits machine reusability
and interoperability. We therefore discuss alternative and complementary approaches to the publication of research data.

Co-authors: Emilie Pasche, Déborah Caucheteur, Alexandre Flament, Pierre-André Michel, Anais Mottaz, Patrick Ruch